Between 1850 and 1855, Robert Remak had further refined the germ cell layer concept, and introduced into English were the terms "mesoderm" by Huxley in 1871 and "ectoderm" and "endoderm" by Lankester in 1873.
Germ layer, primary tissue layer formed during embryogenesis in animals
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To form the streak, reptiles, birds and mammals arrange mesenchymal cells along the prospective midline, establishing the second embryonic axis, as well as the place where cells will ingress and migrate during the process of gastrulation and germ layer formation.