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Since 1999 he has authored and run a variety of clinical trials at the NCI, serving as Principal Investigator or an Associate Investigator on approximately 40 trials.
Many clinical trials have failed in an attempt to develop effective neuroprotective drugs to combat stroke perhaps because those drugs only deal with one aspect of stroke therefore neglecting the fact that stroke is a multifaceted problem.
In July 2009, caBIG announced a collaboration with the Dr. Susan Love Research Foundation to build an online cohort of women willing to participate in clinical trials.
Several clinical trials had been conducted in hospitals (including Singapore General Hospital, Tan Tock Seng Hospital, KK Women’s and Children’s Hospital, Tuen Mun Hospital and Union Hospital) successfully.
Merck has a Cathepsin K inhibitor in Phase 3 clinical trials by the name of Odanacatib for an expected indication of osteoporosis.
Georges Tanret identified an alkaloid (galegine) from Galega officinalis that was evaluated in clinical trials in patients with diabetes in the 1920s and 1930s.
Based on evidence from multiple randomized clinical trials (RCTs), a systematic review published in the Journal of the Royal Society of Medicine (October 2006) stated that CBT and GET interventions showed promising results, appearing to reduce symptoms and improve function.
It is funded by the Effective Health Care Research Programme Consortium, UK (via the British DFID and the International Health Group, Liverpool School of Tropical Medicine) The Indian Council of Medical Research (ICMR), Indiam the Cochrane Schizophrenia Group (via the Department of Health, UK and the University of Nottingham), and the World Health Organization's Clinical Trials in Children group.
Contemporary Clinical Trials, the continuation of Controlled Clinical Trials
Clinical trials by the Liverpool School of Tropical Medicine in June 2005 reported that an 8 week course almost completely eliminated microfilariaemia.
Empagliflozin is drug which is being investigated in clinical trials for the oral treatment of type 2 diabetes by Boehringer Ingelheim and Eli Lilly and Company.
End point of clinical trials, primary and secondary endpoints of clinical trials
Flavocoxid has been associated with liver toxicity in prospective clinical trials published in the Annals of Internal Medicine.
As former chair of the Lymphoma Committee of the Cancer and Leukemia Group B (CALGB), a national American cooperative trials group, Canellos initiated many practice-changing clinical trials of cancer therapies.
Another THR and hip resurfacing system, the DePuy ASR, which had been undergoing clinical trials for hip resurfacing in the United States and marketed overseas, has been recalled as a result of having been proven to have abnormally high revision rates.
For 7 years he was a principal investigator for conducting international multi-centre Food and Drug Administration regulated clinical trials for assessing the safety and efficacy of reproducive technology.
In 1987 Corey directed the AIDS Clinical Trials Group, or ACTG, which conducted pivotal clinical trials confirming the use of the antiretroviral drug AZT to reduce maternal-fetal transmission of HIV and the usefulness of highly active antiretroviral therapy (HAART).
Although clinical trials only revealed an increased risk of insomnia, post-marketing surveillance showed that the drugs are associated with a possible increase in suicidal behavior and other side effects such as agitation, aggression, anxiousness, dream abnormalities and hallucinations, depression, irritability, restlessness, and tremor.
The center is funded by numerous private corporations in the form of clinical trials from such companies as Eli Lilly & Co., Otsuka Pharmaceuticals, and Forest Laboratories.
Lundbeck has licensed the drug from Biotie Therapies and performed clinical trials with nalmefene for treatment of alcohol-dependence.
He is best known for his preclinical development of E1A gene therapy and multiple preclinical development which led to novel clinical trials related to inflammatory breast cancer and triple negative breast cancer.
Corticosteroids have also been investigated for the prevention of PTE, but clinical trials revealed that the drugs did not reduce late PTS and were actually linked to an increase in the number of early PTS.
Sprifermin as another name for human recombinant FGF18 and its manufacturers hope it will soon enter clinical trials for treatment of knee osteoarthritis.
His major contributions have been in the indigenously developed non-hormonal polymer based injectable male contraceptive (RISUG) for which the Final Phase-III Clinical trials are underway; Problem-solving at a national level regarding contraceptives in mass usage, especially Copper T; individualized spot air-conditioning system for hospital patients and rehabilitation of the blind, with emphasis on opening automobile repair as an employment avenue.
The award is the highest tribute presented by the Foundation Fighting Blindness, a nonprofit organization that funds research and clinical trials on eye disease.
The latter two (axitinib and pazopanib) are in clinical trials, the results of which were presented (June 7) at the American Society of Clinical Oncology meeting.
One derivative of it, compound name IPI-926, is currently undergoing clinical trials for the treatment of various types of cancer, including hard-to-treat hematologic malignancies, chondrosarcoma, and pancreatic cancer.
The building houses the School for Medicine and Health and the North East Public Health Observatory, as well the Centre for History of Medicine and Disease, the Cognitive Neuroscience Research Unit (Department of Psychology), the Durham Endocrinology Laboratory (Department of Anthropology), the Durham University Clinical Trials Unit and researchers from the Geography department.
Zelen's design, experimental design for randomized clinical trials proposed by statistician Marvin Zelen